Abstract Background Cancer molecular subtyping plays a critical role in individualized patient treatment.In previous studies, high-throughput gene expression signature-based methods have been proposed to identify cancer subtypes.Unfortunately, the existing ones suffer from the curse of dimensionality, data sparsity, and computational deficiency.Met
Host cell invasion by apicomplexan pathogens such as Blankets the malaria parasite Plasmodium spp.and Toxoplasma gondii involves discharge of proteins from secretory organelles called micronemes and rhoptries.In Toxoplasma a protein complex comprising the microneme apical membrane antigen 1 (AMA1), two rhoptry neck proteins, and a protein called Ts
The COVID-19 pandemic has disrupted the global food supply chain and exacerbated the problem of food and nutritional insecurity.Here we outline soil strategies to strengthen local food production systems, enhance their resilience, and create a circular economy focused on soil restoration through carbon sequestration, on-farm cycling of nutrients, E
The solvent-assisted lipid bilayer (SALB) formation method provides a simple and efficient, microfluidic-based strategy to fabricate supported lipid bilayers (SLBs) with rich compositional diversity on a wide range of solid supports.While various studies have been performed to characterize SLBs formed using the SALB method, relatively limited work
In agricultural production, temperature and moisture are important factors affecting grain yield and quality.Although moderate drought at the grain-filling stage can effectively alleviate the damage caused by high temperature, the specific regulatory mechanism driving the effect of moderate drought at the high temperature on starch synthesis is sti